Description
Product Characteristics: The kit is a competitive inhibition enzyme immunoassay technique for the in vitro quantitative measurement of butyrylcholinesterase in mouse serum, plasma, tissue homogenates, cell lysates, cell culture supernates.
Target Information: Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq, Jul 2008]